Werner's syndrome

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Information for Authority record
Name (Hebrew)
תסמונת ורנר
Name (Latin)
Werner's syndrome
Other forms of name
Adult progeria
Progeria, Adult
Werner syndrome
See Also From tracing topical name
Progeria
Syndromes
MARC
MARC
Other Identifiers
Wikidata: Q1154619
Library of congress: sh 85146124
Wikipedia description:

Werner syndrome (WS) or Werner's syndrome, also known as "adult progeria", is a rare, autosomal recessive disorder which is characterized by the appearance of premature aging. Werner syndrome is named after the German scientist Otto Werner. He identified the syndrome in four siblings observed with premature aging, which he explored as the subject of his dissertation of 1904. It has a global incidence rate of less than 1 in 100,000 live births (although incidence in Japan and Sardinia is higher, affecting 1 in 20,000–40,000 and 1 in 50,000, respectively). 1,300 cases had been reported as of 2006. Affected individuals typically grow and develop normally until puberty; the mean age of diagnosis is twenty-four, often realized when the adolescent growth spurt is not observed. The youngest person diagnosed was six years old. The median and mean ages of death are 47–48 and 54 years, respectively. The main causes of death are cardiovascular disease and cancer.

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